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These findings identify a novel post-infarction therapy for amelioration of the adverse effects of tobacco exposure on the infracted myocardium and advocate the use of dietary supplement antioxidants for habitual smokers to prevent and reverse cardiovascular adverse effects in the absence of successful achievement of cessation of smoking

In conclusion pyroglutamate acidosis should be considered in the differential diagnosis of a patient presenting with an unexplained high anion gap acidosis, particularly in the high-risk patient groups 7

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An alternative model for As methylation (Figure 1b) has been proposed (Hayakawa et al., 2005, Naramandura et al., 2006)